Get out of the subway at Marquês de Pombal and start going down towards Liberdade Avenue, the city's most charming street.
You will arrive at Praça dos Restauradores. A little bellow, you will find the train station and Rossio Square.
Continue walking until you find Augusta Street. Right at the end of it, you will see the Museum of Fashion and Design and the Triumphal arch.
Once you have crossed the Triumphal arch, you'll arrive at Praça do Comércio, the country's largest square. Take a minute to enjoy the view to the river Tagus from Cais das Colunas.
Take a break to have lunch in one of the many restaurants on Praça do Comércio, also known as Terreiro do Paço.
After lunch, go up until you get to Conceição Street. There you will catch tram number 28 towards Martim Moniz.
You'll pass by the Sé of Lisbon but you should only hop off the tram at Largo das Portas do Sol. Take a break to enjoy another great view over the city and then start walking up until São Jorge’s Castle.
Take a walk through the castle old walls. After that, go down towards the labyrinthine streets of Alfama neighborhood.
Start walking backwards to Praça do Comércio once again. Tram number 15 will pass in front of the Triumphal arch and you must catch it: direction Belém.
The journey is short. Take one more break to have a taste of one of the typical delicacies of the Portuguese gastronomy: it is called pastel de nata and you'll get them at a place called "Pastéis de Belém". Take yours outside and have a bite in the garden across the street.
With your energy recovered, walk towards the impressive Jerónimos Monastery. Once inside, do not forget to visit the stone cloister and the tomb of the navigator Vasco da Gama.
Go ahead into Padrão dos Descobrimentos and Tower of Belém and feel free to enjoy the sunset with the river Tagus behind, making the perfect set.
To finish on a high note, have dinner in one of the restaurants in Belém or go back to the center of the city to try one of the classics Fado houses, placed in Alfama or at Bairro Alto.
Get out of the subway at Rato (yellow line) and start walking until Príncipe Real, a very trendy neighbourhood filled with new stores and concepts. You can have something to eat in one of the kiosks in the garden.
Walk down towards the viewpoint of São Pedro de Alcântara and take a look around the city view. And continuing down, you will find the statue of Fernando Pessoa at the A Brasileira café.
Passing through Largo Camões, go up into Loreto Street and continue walking to Santa Catarina viewpoint, also known as “Adamastor”.
Go back to Calçada do Combro and continue to go down until you get to Santos neighbourhood, where you will find a hub of designers and decoration stores (Santos Design District).
Grab tram number 15 and leave in Alcantâra stop. Look for LX Factory, an old industrial area that was adapted into a centre of artistic innovation. Here you have many good options to a lunch break.
After lunch, take the bus number 756 and leave at Berna Avenue. There you will find the fabulous gardens of Calouste Gulbenkian Foundation, where you can visit many expositions and have a coffee.
Go ahead to Avenida da República and walk by your right side, so you can see Praça do Saldanha. A little ahead at Fontes Pereira de Melo Avenue, you will find street art on old and abandoned buildings.
Go back to República Avenue towards Campo Pequeno and the Bull Ring. There are some good restaurants around — and also Culturgest, where you will be able to watch concerts and other shows.
Fancy a drink? Wait for the subway and go to Bairro Alto (Baixa-Chiado, blue line) and Bica Street. Later, go down Alecrim Street towards Cais do Sodré to continue the night. If you have any doubts, just follow the crowd!